Tag Archives: protein expression

Technology

Oxford Expression Technologies Launch Streamlined Transfection Technology

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Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, launches flashFECTIN™, a transfection reagent optimized for insect cell lines.

Oxford, UK, May 14, 2013 – Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, launches flashFECTIN™, a transfection reagent optimized for insect cell lines. Used in conjunction with the world renowned flashBAC™ system, the new reagent represents significant improvements with respect to ease of use, speed and affordability.

Co-transfections can be troublesome and time consuming, flashFECTIN™ has been specifically designed to address these issues, the co-transfection protocol has been highly streamlined to allow the fastest flashBAC™ reaction times to date whilst still maintaining the high efficiencies expected from the flashBAC™ system. The new transfection reagent is a non-lipid based formulation that is non-toxic to cells and is specifically optimized for insect cell lines Sf9, Sf21 and Tni.

Passing comment, James Bernard, Commercial Director at Oxford Expression Technologies said, “We are pleased to announce the launch of flashFECTIN™, our new transfection reagent to further improve the flashBAC™ system” he continued, “we are delighted that our customers can now benefit from a more affordable system with a faster and simplified protocol that still produces the same high transformation efficiencies.”

Oxford Expression Technologies invites anyone with an interest in baculovirus protein expression to visit their website – http://oetltd.com/

Oxford Expression Technologies is a biotechnology company specializing in the use of baculovirus vectors, a eukaryotic expression system that can express a large variety of recombinant proteins. Oxford Expression Technologies provides recombinant protein expression products, services and consultancy to many global pharmaceutical companies. The Company’s proprietary flashBAC technology enables large amounts of a given protein to be produced in culture. Its internationally renowned expertise and products enable proteins to be produced faster, more easily and cost-effectively using automated and high-throughput methods compared with other baculovirus expression systems. This contributes to the development of new drugs and research targeted towards understanding how proteins work in health and disease.

The company was founded in 2007 as a result of collaboration between Oxford Brookes University and the Natural Environment Research Council to provide researchers with custom proteins for research purposes.

For Further information or an illustrative image:
Media contact – Mathew Taylor, Director, Algorythm Solutions Ltd, mobile: +44 (0)773 403 2112, email: mtaylor@algorythmsolutions.com, website: www.algorythmsolutions.com

Contact:
Mathew Taylor
Director
Algorythm Solutions Ltd
10 Torkington St
Stamford, Lincolnshire PE9 2UY
+44 (0)773 403 2112
mtaylor@algorythmsolutions.com

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Is it a Moment or an Abuse: the Boom of iPSCs Research after 2012 Medicine Nobel Prize

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On Creative Biomart website, we can read a report about the 2012 Nobel Prize in Physiology or Medicine regarding the two winners. They bring hope for organ or tissue repair for human or even for rejuvenation, i.e. for long life through induced pluripotent stem cells (iPSCs).

Since the first appearance in 2006, iPSCs became the hit and focus. But there are still lots of unknowns waiting for us before achieving the ideal status. Thus, numerous scientists, researchers and businessmen are struggling and investing for that goal. Here are some examples:

On Dec. 5, 2012, Roche (SIX: RO, ROG; OTCQX: RHHBY) and the Innovative Medicines Initiative (IMI) announced today the launch of StemBANCC, a new academic–industry partnership that unites ten pharmaceutical companies and 23 academic institutions. Initiated and coordinated by Roche and managed by Oxford University, StemBANCC aims to use human induced pluripotent stem cells as research tools for drug discovery with the goal of using this ground-breaking new technology to develop human disease models and enhance drug development.

On Oct. 29, 2012, on the PANS Journal there is an article about Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells.

On Oct. 4, 2012, on Cell Stem Cell, there is a report with the title be Genome Sequencing of Mouse Induced Pluripotent Stem Cells Reveals Retroelement Stability and Infrequent DNA Rearrangement during Reprogramming.

On Jan. 30, 2012, on the PANS Journal, there is a report about modeling hepatitis C virus infection using human induced pluripotent stem cells, which make the individual and tailor therapy further.

Above are only a small part of such studies. People still wonder does it is the moment or an abuse on the iPSCs research. When someone reviewed one of the winners, Shinya Yamanaka, about his opinion on the challenge of iPSCs research, he said, “I have two research directions, the first is to establish human iPSCs bank that comply with clinical application standards. The second is to study the cell mechanism of iPSCs regenerating. And I think the current threat is still to be the safety problem as good research respects both scientific and ethical standards.”

But no one deny the great potential of iPSCs.

About Creative Biomart
Creative Biomart has a long history in ELISA kits; its products are available in a range of formats including colorimetric, fluorescence, and chemiluminescence-based kits for various types of Analyte.

In addition, Creative biomart also provides protein expression, PEGylation service,custom cDNA clone and other services. It provides the largest number of cDNA clones in multiple sets of vector systems with various features, including more than two hundred thousand cNDA clones. In peer industry, Creative Biomart has good reputation with technical and price advantage. In 2010, its global sales reach 26 billion.

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Contact Details: 45-16 Ramsey Road, Shirley, NY 11967, USA Websitehttp://www.creativebiomart.net mail: serenachang5236@gmail.com
Technology

Oxford Expression Technologies Launch Innovative Virus Like Particle Expression Vector

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Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, announce the launch of flashBACPRIME, the newest edition to the flashBAC range.

Oxford, UK, November 27, 2012 – Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, announce the launch of flashBACPRIME, the newest edition to the flashBAC range. The new vector is specifically designed to provide increased virus like particle yield and recovery, and also benefits from the traditional ease of use associated with the renowned flashBAC one step baculovirus expression system.

The new vector offers an innovative solution to one of the challenges of VLP production by providing scientists with enhanced recovery and yield. The performance improvement is achieved by inducing cell lysis at a very late stage of infection in Trichoplusia ni (T.ni) derived cell lines. The flashBACPRIME expression vector also offers flexibility for users, although designed for use in virus like particle production, it can also be used for cytoplasmic protein expression and production.

Passing comment, James Bernard, the CEO at Oxford Expression Technologies said, “We are pleased to announce the launch of flashBACPRIME, it represents a significant improvement in performance and we are delighted to offer these benefits to our customers” he continued, “Yield and recovery are an inherent concern with VLP production and our new technology provides scientists with a solution that addresses these concerns, we are also pleased to add another innovation to our highly successful flashBAC range.”

Oxford Expression Technologies invites anyone with an interest in baculovirus protein expression and virus like particle production to visit their website – http://oetltd.com/

Oxford Expression Technologies is a biotechnology company specializing in the use of baculovirus vectors, a eukaryotic expression system that can express a large variety of recombinant proteins. Oxford Expression Technologies provides recombinant protein expression products, services and consultancy to many global pharmaceutical companies. The Company’s proprietary flashBAC technology enables large amounts of a given protein to be produced in culture. Its internationally renowned expertise and products enable proteins to be produced faster, more easily and cost-effectively using automated and high-throughput methods compared with other baculovirus expression systems. This contributes to the development of new drugs and research targeted towards understanding how proteins work in health and disease.

The company was founded in 2007 as a result of collaboration between Oxford Brookes University and the Natural Environment Research Council to provide researchers with custom proteins for research purposes.

For Further information or an illustrative image:
Media contact – Mathew Taylor, Director, Algorythm Solutions Ltd, mobile: +44 (0)773 403 2112, email: mtaylor@algorythmsolutions.com, website: www.algorythmsolutions.com

Contact:
Mathew Taylor
Director
Algorythm Solutions Ltd
10 Torkington St
Stamford, Lincolnshire PE9 2UY
+44 (0)773 403 2112
mtaylor@algorythmsolutions.com

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Technology

Oxford Expression Technologies Launch Revolutionary Baculovirus Extraction and Quantification Kit

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Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, launches baculoQUANT ALL-IN-ONE™, a baculovirus extraction and titration kit.

Oxford, UK, March 26, 2012 – Oxford Expression Technologies (OET), the award-winning specialist provider of baculovirus-based protein expression solutions, launches baculoQUANT ALL-IN-ONE™, a baculovirus extraction and titration kit. The new kit has been developed together with PCR reagent and equipment specialists Agilent Technologies as a continued theme to provide ease of use to scientists. baculoQUANT ALL-IN-ONE contains all the necessary components for baculovirus extraction and quantification and provides significant advantages over traditional methods.

The new kit represents a significant step forward for baculovirus quantification as it bypasses the need for DNA extraction spin columns, plaque assays, ELISA and immuno assays that current methods rely on. It also boasts a host of new features including viral DNA extraction and titration in less than three hours, less than 1 hour hands on time, increased accuracy and one step DNA extraction.

Passing comment, Richard Broadhead, Sales and Marketing Manager at Oxford Expression Technologies said, “We are pleased to announce the launch of the baculoQUANT ALL-IN-ONE™ baculovirus quantification kit, it represents our continued commitment to provide innovation and ease of use to our customers and scientists involved in recombinant protein expression,” he continued, “We have increased the speed and simplified a key part of any baculovirus workflow, the quantification of virus, we are delighted that our customers can benefit from these improvements.”

Agilent Technologies’ Paige Weis, Manager Custom and Bulk Services commented, “ We are very pleased to collaborate with Oxford Expression Technologies in the development of the new baculoQUANT ALL-IN-ONE™kit, Agilent Technologies is a global leader in PCR technologies and we are delighted to contribute our high performance and easy to use PCR components to this exciting new kit.”

Oxford Expression Technologies invites anyone with an interest in baculovirus protein expression to visit their website – http://oetltd.com/

Agilent Technologies is a world renowned PCR reagent and equipment specialist and one of the world’s premier measurement companies specializing in three key areas, Chemical Analysis, Life Sciences and Electronic Measurement.

Oxford Expression Technologies is a biotechnology company specializing in the use of baculovirus vectors, a eukaryotic expression system that can express a large variety of recombinant proteins. Oxford Expression Technologies provides recombinant protein expression products, services and consultancy to many global pharmaceutical companies. The Company’s proprietary flashBAC technology enables large amounts of a given protein to be produced in culture. Its internationally renowned expertise and products enable proteins to be produced faster, more easily and cost-effectively using automated and high-throughput methods compared with other baculovirus expression systems. This contributes to the development of new drugs and research targeted towards understanding how proteins work in health and disease.

The company was founded in 2007 as a result of collaboration between Oxford Brookes University and the Natural Environment Research Council to provide researchers with custom proteins for research purposes.

Contact:
Mathew Taylor
Director
Algorythm Solutions Ltd
10 Torkington St, Stamford
Lincolnshire PE9 2UY
+44 (0)773 403 2112
mtaylor@algorythmsolutions.com

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