Tag Archives: flash purification

New Biotage® SNAP ULTRA C18 Cartridges – High Performance Reversed Phase Flash Purification

November 11, 2014 staronepr Leave a comment

Biotage announces the launch of Biotage® SNAP ULTRA C18 – a range of high performance, reversed phase flash purification cartridges and samplets.

Uppsala, Sweden (November 11, 2014) — Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of Biotage® SNAP ULTRA C18 – a range of high performance, reversed phase flash purification cartridges and samplets.

Biotage® SNAP ULTRA C18 reversed phase cartridges are optimized for use with Biotage ACI™ and Isolera™ flash systems and are available in 12 g, 30 g, 60 g, 120 g, 400 g, 950 g and 1850 g cartridge sizes. They enable chemists to confidently load 2-3% weight percentage of samples onto reversed phase columns, a marked improvement when compared to the currently typical 0.5 – 1% loads. The time taken for purification and solvent usage can therefore be reduced by 50% or a smaller cartridge can be used for the same purification, often with improved purification results.

The new reversed phase cartridges are packed with the new, Biotage® HP-Sphere C18 25 micron spherical silica particles that give a boost to resolution with higher purity peaks over standard reversed phase cartridges. The silica is chemically neutral with no adverse interactions, ensuring higher yields and better recoveries; a wide diversity of purifications are possible, including the use of both acidic or basic modifiers.

“It is no longer enough for suppliers to arbitrarily work on single aspects of the workflow and purification – today a more holistic approach is required, one that involves a combination of factors; with this product range we have further augmented the Biotage ACI™ and Isolera™ flash systems and have created a superior product for purification” says Dr. Sunil Rana, Global Product Manager, Biotage.

For further information, visit http://www.biotage.com or call:
In Europe: +46 18 56 57 10
In North America: (Toll Free) 1 800 446 4752
In Japan: +81 422 28 1233
Other areas, please call: +46 18 56 57 10

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For further press information at Biotage, please contact:
James Churchill
Marketing Communications
Biotage GB Limited
Distribution Way
Dyffryn Business Park
Ystrad Mynach
Hengoed, Wales CF82 7TS
United Kingdom
Tel: +44 (0)1443 811 849
Mobile: +44(0)7875484778
Email: james.churchill@biotage.com

About Biotage
Biotage offers solutions, knowledge and experience in the areas of analytical and medicinal chemistry. Customers include the world’s top pharmaceutical and biotechnology companies, as well as leading academic institutes. The company is headquartered in Uppsala, Sweden, with offices in China, Japan, the United Kingdom, the United States and a worldwide network of distributors. Biotage has 290 employees with sales of 444.6 MSEK in 2013. Biotage is listed on the NASDAQ OMX Nordic Stock Exchange. Website: http://www.biotage.com.

Biotech

Biotage Launches ACI™ – Accelerated Chromatographic Isolation

July 11, 2014 staronepr Leave a comment

Biotage announces the launch of ACI™ (Accelerated Chromatographic Isolation), a new advance converting simple flash purification into a faster and more economical way to isolate pure compounds.

Uppsala, Sweden (July 10, 2014) — Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of ACI™ (Accelerated Chromatographic Isolation), a new advance converting simple flash purification into a faster and more economical way to isolate pure compounds.

Biotage believes that ACI™ will radically improve the efficiency of the laboratory, embracing the latest developments in purification technology to guide chemists towards improved chromatography. With running costs a concern in most laboratories, ACI™ will efficiently move users to the end-point even faster. Traditional purification taking more than 15 minutes is reduced to 5 minutes; a 250 mg scale laboratory scale experiment can now be purified in less than 3 minutes on a 10 g column with an ACI™ enabled Biotage Isolera™ flash purification system.

“This is a very exciting and pivotal development, the speed enhancements are akin to the impact felt when microwaves first hit the scene. There is nothing out there that comes close to this system. Chemists will now have freedom to work on other things while they let their ACI™ system do the purification. It is fully automated, reliable and lightning fast, we can completely purify 250 mg of sample in less than 3 minutes, this is quicker than most people take to run the TLC” says Dr Sunil Rana, Global Product Manager, Biotage.

Biotage Isolera™ systems already recommend cartridges based on the sample size and programmed TLC data; they work out the best solvent gradient based on compound, and provide real time indication of eluting compounds, using UV, ELSD or Mass Detection. They subtract signal baselines automatically, so chemists can be confident that the correct fractions are collected.

ACI™ radically improves this, working seamlessly with the Biotage Isolera™ system, the simple wizard quickly guides chemists through the system, beneficial for new users or those whose expertise or priorities lie in synthesis rather than purification. Existing Biotage Isolera systems can be upgraded to ACI™ systems, and ACI™ will come as standard on all new production systems.

For further information visit http://www.biotage.com or call:
In Europe: +46 18 56 57 10
In North America: (Toll Free) 1 800 446 4752
In Japan: +81 422 28 1233
Other areas, please call: +46 18 56 57 10

-Ends-

For further press information from Biotage please contact:
James Churchill
Marketing Communications
Biotage GB Limited
Distribution Way
Dyffryn Business Park
Ystrad Mynach
Hengoed, Wales CF82 7TS
United Kingdom
Tel: +44 (0)1443 811 849
Mobile: +44(0)7875484778
E-Mail: james.churchill@biotage.com

Biotech

Biotage Moving Into Mass Directed Flash

September 25, 2012 staronepr Leave a comment

Biotage® (STO: BIOT), announces that Biotage is in late stage development with its partner Microsaic Systems plc of a fully integrated solution for Mass Directed Flash with Biotage’s flagship flash purification system Isolera™.

Uppsala, Sweden, September 25, 2012 — Biotage® (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces that Biotage is in late stage development with its partner Microsaic Systems plc of a fully integrated solution for Mass Directed Flash with Biotage’s flagship flash purification system Isolera™. A presentation will be held at the JASIS meeting in Makuhari, Japan on 5th September, 2012. The new solution will become commercially available in early 2013.

“This is a game changer in flash purification that will allow chemists to significantly improve their work flow. We have high expectations on the forthcoming launch of this product that will further strengthen our purification business,” says Toshiyuki Yachi, Vice President of Marketing.

-Ends-

For further press information at Biotage please contact:
James Churchill
Marketing Communications
Biotage GB Limited
Distribution Way
Dyffryn Business Park
Ystrad Mynach
Hengoed, Wales CF82 7TS
United Kingdom
Tel: +44 (0)1443 811 849
Mobile: +44(0)7875484778
E-Mail: james.churchill@biotage.com

About Biotage
Biotage offers solutions, knowledge and experience in the areas of analytical and medicinal chemistry. Customers include the world’s top pharmaceutical and biotechnology companies, as well as leading academic institutes. The company is headquartered in Uppsala, Sweden, with offices in China, Japan, the United Kingdom, the United States and a worldwide network of distributors. Biotage has 272 employees with sales of 428.9 MSEK in 2010. Biotage is listed on the NASDAQ OMX Nordic Stock Exchange. Website: http://www.biotage.com.

Biotech

Biotage unveils Isolera Spektra with full PDA Spectral Scanning

April 12, 2012 staronepr Leave a comment

Biotage, a leading global supplier of solutions and technology for analytical and medicinal chemistry, introduced Isolera™ Spektra.

Uppsala, Sweden, April 12, 2012 — Biotage® (STO: BIOT), a leading global supplier of solutions and technology for analytical and medicinal chemistry, introduced Isolera™ Spektra. The new Isolera™ Spektra expands the scope of application of Biotage’s market-leading Flash Chromatography product line by increasing efficiency with significant solvent and time saving capabilities as well as enabling purity assessment technology.

The new full PDA spectral scanning capability with ?-All detection and baseline correction generates real-time PDA spectral data for eluting compounds. This provides compound detection at any wavelength, enabling chemists to see how pure their eluting compounds are in both real-time and post-purification. Post-purification spectral analysis can also be conducted in both two dimensional and three dimensional displays for improved visibility of impurities and eliminating the need for post-flash TLC purity testing.

The new proprietary TLC-to-Step gradient feature (patent-pending) instantly converts TLC separation data into an efficient step gradient and suggests a sample load for up to six compounds. Chemists can target one or more compounds for isolation, dramatically reducing solvent requirements and purification time compared to linear gradients. Used in conjunction with Biotage® SNAP Ultra cartridges with their 2-3X loading capacity and flow rate advantage, researchers can routinely achieve total processing times and ultra-low solvent consumption volumes which previously were not possible with other flash instruments.

“Isolera™ Spektra is a revolutionary enhancement in flash purification. It transforms 1-dimensional flash purification into 3D purification systems that can target a specific compound for isolation and characterize collected fractions for purity and spectral properties” says Bob Bickler, Senior Product Manager, Biotage®. “This technology can have a huge positive impact on the amount of time that researchers need to invest in compound purification as well as the solvents they consume. These system improvements combined with high efficiency columns will quickly pay for themselves in any lab”.

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About Biotage
Biotage offers solutions, knowledge and experience in the areas of analytical and medicinal chemistry. Customers include the world’s top pharmaceutical and biotechnology companies, as well as leading academic institutes. The company is headquartered in Uppsala, Sweden, with offices in China, Japan, the United Kingdom, the United States and a worldwide network of distributors. Biotage has 272 employees with sales of 428.9 MSEK in 2010. Biotage is listed on the NASDAQ OMX Nordic Stock Exchange. Website: http://www.biotage.com